Evolutionary selection of personalized melanoma cell/tissue dual-homing peptides for guiding bionanofibers to malignant tumors.
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| Abstract | :
Both melanoma cells and tissues were allowed to interact with an identical pool of billions of human-safe phage nanofiber clones with each genetically displaying a unique 12-mer peptide at the tips, respectively, resulting in the discovery of bionanofibers displaying a melanoma cell/tissue dual-homing peptide for personalized targeted melanoma therapy. |
| Year of Publication | :
2018
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| Journal | :
Chemical communications (Cambridge, England)
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| Date Published | :
2018
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| ISSN Number | :
1359-7345
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| DOI | :
10.1039/c7cc09077c
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| Short Title | :
Chem Commun (Camb)
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