C3 glomerulonephritis secondary to mutations in factors H and I: rapid recurrence in deceased donor kidney transplant effectively treated with eculizumab.
| Author | |
|---|---|
| Abstract | :
C3 glomerulonephritis (C3GN) is caused by alternate complement pathway over-activation. It frequently progresses to end-stage renal disease, recurs in two-thirds of transplants and in half of these cases progresses to allograft loss. There is currently no proven treatment for C3GN. |
| Year of Publication | :
2018
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| Journal | :
Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association
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| Date Published | :
2018
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| ISSN Number | :
0931-0509
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| URL | :
https://academic.oup.com/ndt/article-lookup/doi/10.1093/ndt/gfx369
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| DOI | :
10.1093/ndt/gfx369
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| Short Title | :
Nephrol Dial Transplant
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